URIC ACID
URIC ACID
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Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations of uric acid can lead to gout and are associated with other medical conditions, including diabetes and the formation of ammonium acid urate kidney stones.
A normal concentration range of uric acid (or hydrogen urate ion) in human blood is 25 to 80 mg/L for men and 15 to 60 mg/L for women. (but see below for slightly different values). An individual can have serum values as high as 96 mg/L and not have gout. In humans, about 70% of daily uric acid disposal occurs via the kidneys, and in 5–25% of humans, impaired renal (kidney) excretion leads to hyperuricemia. Normal excretion of uric acid in the urine is 270 to 360 mg per day (concentration of 270 to 360 mg/L if one litre of urine is produced per day – higher than the solubility of uric acid because it is in the form of dissolved acid urates), roughly 1% as much as the daily excretion of urea.
In human blood plasma, the reference range of uric acid is typically 3.4–7.2 mg per 100 mL(200–430 μmol/L) for men, and 2.4–6.1 mg per 100 mL for women (140–360 μmol/L). Uric acid concentrations in blood plasma above and below the normal range are known as, respectively,
Genetics
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Although foods such as meat and seafood can elevate serum urate levels, genetic variation is a much greater contributor to high serum urate. A proportion of people have mutations in the urate transport proteins responsible for the excretion of uric acid by the kidneys.
Cardiovascular disease
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Hyperuricemia is associated with an increase in risk factors for cardiovascular disease. It is also possible that high levels of uric acid may have a causal role in the development of atherosclerotic cardiovascular disease.
Uric acid stone formation
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Kidney stones can form through deposits of sodium urate microcrystals.
Saturation levels of uric acid in blood may result in one form of kidney stones when the urate crystallizes in the kidney.
AYURVEDIC FORMULA
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With water kept overnight in an earthen pot.
Take out a glass of water in a glass tumbler.
One spoon of apple vinegar is mixed in it.
Do not use any metal.If needed, you can take another small glass.To mix apple cider vinegar with water.
Apple vinegar should be of good quality. Must be in a glass bottle.
Mixing vinegar in a glass of water before every meal half an hour ago.
Within 15 days your uric acid will start coming under control.
By changing lifestyle and habits enjoy happy and healthy life.
Thanks to all
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